Injections for Ulcerative Colitis: What You Should Know

At Nasseri Clinic of Arthritic and Rheumatic Diseases, we specialize in the diagnosis and management of autoimmune and inflammatory conditions, such as rheumatoid arthritis, psoriatic arthritis, and other rheumatic diseases. Similar to the treatment of ulcerative colitis, many of these conditions benefit from injectable medications that target the immune system and help control inflammation.
 
How Injections Help Manage Rheumatic Diseases
Injectable therapies are a cornerstone in the management of various arthritic and rheumatic diseases. These medications, which include biologics and immunosuppressants, are delivered directly into the body—either under the skin (subcutaneous), into a muscle (intramuscular), or through the veins (intravenous infusion). This method allows for rapid and efficient absorption, making them especially useful for patients who may have difficulty tolerating or absorbing oral medications.
 
Targeted Immune Modulation
The injectable drugs we use at Nasseri Clinic are designed to target specific components of the immune system that are overactive in conditions like rheumatoid arthritis and other autoimmune diseases. For example, anti-TNF agents such as adalimumab and infliximab, as well as other biologics, block key inflammatory pathways. By doing so, they help reduce joint pain, swelling, and prevent long-term joint damage.
 
Personalized Treatment Plans
The choice of injectable medication, as well as the frequency and method of administration, is tailored to each patient’s individual needs and the severity of their disease. Some injections are given at home, while others require administration at our clinic under medical supervision. Regular monitoring is essential to ensure optimal response to therapy and to manage any potential side effects.
 
Benefits of Injectable Therapy
For many patients with rheumatic diseases, injectable therapies can quickly reduce inflammation, promote healing, preserve joint function, and improve overall quality of life. These medications have transformed the treatment landscape, offering effective options for patients who may not have achieved adequate control with traditional oral medications.

For patients whose disease is not adequately controlled with oral medications, rectal therapies, or less intensive treatments, injectable medications may be recommended—especially for those with moderate to severe disease activity.

Injectable therapies are considered when patients have not responded well to first-line treatments, have experienced significant side effects from oral medications, or require a rapid and effective reduction in inflammation due to the severity of their condition.
 
At Nasseri Clinic, our rheumatology and immunology specialists carefully assess each patient’s medical history, treatment response, and overall health before recommending injectable medications. We recognize the importance of patient preferences and shared decision-making in managing chronic diseases. Whether you are experiencing a flare, have developed resistance to previous therapies, or need a new approach to controlling your symptoms, our team is here to guide you through the available options.

At Nasseri Clinic of Arthritic and Rheumatic Diseases, we specialize in diagnosing and managing immune-mediated and inflammatory conditions, such as ulcerative colitis, which can overlap with rheumatologic diseases. For patients with ulcerative colitis, injectable therapies like biologics and immunosuppressants play a key role in comprehensive care.

Targeted Immune Modulation
Injectable medications for ulcerative colitis target specific immune components, similar to those used for rheumatoid arthritis. These therapies can control both gut and joint inflammation, helping achieve remission.

Convenience and Consistency
Unlike daily oral medications, injectables are administered at regular intervals, improving adherence and maintaining consistent therapeutic levels. This supports stable disease control, especially for patients managing multiple chronic conditions.

Alternative for Non-responders or Side Effects
For patients who don’t respond to oral medications or face side effects, injectables provide an alternative with different mechanisms. Our clinic closely monitors patients for efficacy and safety, tailoring therapy to individual needs.

Reducing Steroid Dependence
Injectable biologics can reduce or eliminate the need for steroids, lowering the risk of steroid-related side effects like osteoporosis.

Improving Overall Quality of Life
By controlling inflammation, injectable therapies reduce the risk of flares, hospitalizations, and surgeries, enhancing overall well-being.

At Nasseri Clinic, our rheumatologists carefully assess patients with ulcerative colitis to determine if injectable medications are appropriate. This includes reviewing the patient’s medical history, symptoms, disease severity, and response to previous treatments. Injectable therapies like biologics or immunomodulators are considered when oral or topical medications fail, cause side effects, or are unsuitable.

We also evaluate inflammation in the colon, joints, and other organs using colonoscopy reports, imaging, and lab tests. Many injectable therapies for ulcerative colitis are also effective for arthritis and autoimmune diseases, allowing for an integrated treatment approach.

Before recommending injection therapy, we review the patient’s overall health, including risk factors such as infections, tuberculosis, and coexisting conditions. We discuss the potential risks and benefits, administration methods (self-injections versus clinic infusions), and the importance of monitoring.

Patient preferences, lifestyle, and comfort with injections are key factors in our shared decision-making process. Our goal is to provide personalized care with evidence-based treatments. Regular follow-ups ensure treatment effectiveness, manage side effects, and support your long-term health and quality of life.

For patients with moderate to severe ulcerative colitis, Dr. Nasser Nasseri offers advanced injection and infusion therapies using biologic medications to target inflammation directly. These therapies, administered under supervision or sometimes at home, are utilized for complex cases and associated conditions, with the clinic providing a safe environment for treatments.
 
Contact Nasseri Clinic today to learn more about how our injection treatments can help manage your ulcerative colitis and improve your well-being. For more information, contact us or request an appointment online. We serve patients from Columbia MD, Glen Burnie MD, Edgewater MD, North Baltimore MD, Hebbville MD, Woodlawn MD, Pasadena MD, Jacobsville MD, Ellicott City MD, Laurel MD, Dundalk MD, Halethorpe MD, Overlea MD, Parkville MD, Riva MD, Annapolis MD, Ferndale MD, and surrounding areas.